Approach Vancouver on Highway 1 (the Trans-Canada Highway). After passing through New Westminster and Burnaby, take the Grandview Highway exit. (You're close to the Grandview Highway exit after you pass the exit to Simon Fraser Univerity -- Gaglardi Way --, then the Willingdon exit is next, and then the Grandview Highway exit. Don't miss it, the next exit puts you in downtown Vancouver.)
The Grandview Highway quickly becomes a typical Vancouver avenue, 12th Avenue. Continue west along 12th Avenue for about 20-25 minutes. You will pass the Vancouver City Hall (at Cambie Street), and then the Vancouver General Hospital. Immediately following the VGH, turn left on to Oak Street, heading south. Continue south on Oak St. briefly, turning right on 16th Ave. Turn right on to Wolfe Ave. Wolfe Ave turns into 16th Ave. again as you cross Granville Street. Continue west along 16th Ave. until you approach the University (15-20 min. drive). Turn right on to East Mall, and continue along East Mall to find parking.
